Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695681 | 0.90 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DMCHR1 | |
| SCHEMBL7699175 | 0.87 | MCHR1 (0.45) | PDE4APDE4BPDE4CPDE4DMCHR1 | |
| SCHEMBL7698759 | 0.87 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DMCHR1 | |
| SCHEMBL7700748 | 0.85 | MCHR1 (0.44) | PDE4APDE4BPDE4CPDE4DMCHR1 | |
| SCHEMBL7700767 | 0.85 | MCHR1 (0.42) | PDE4APDE4BPDE4CPDE4DMCHR1 | |
| SCHEMBL7693775 | 0.84 | MCHR1 (0.44) | PDE4APDE4BPDE4CPDE4DMCHR1 | |
| SCHEMBL7699082 | 0.83 | MCHR1 (0.43) | PDE4APDE4BPDE4CPDE4DMCHR1 | |
| SCHEMBL7696526 | 0.83 | MCHR1 (0.41) | PDE4APDE4BPDE4CPDE4DMCHR1 | |
| SCHEMBL7700309 | 0.83 | MCHR1 (0.44) | PDE4APDE4BPDE4CPDE4DMCHR1 | |
| SCHEMBL7701516 | 0.83 | MCHR1 (0.42) | PDE4APDE4BPDE4CPDE4DMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |