Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.65 |
| ▸ | HTR2C | P28335 | 2/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7259921 | 0.91 | ADRA1D (0.70) | ADRA1DHTR2CADRB2SLC6A4 | |
| SCHEMBL13261751 | 0.88 | HTR2C (0.68) | ADRA1DHTR2CADRB2SLC6A4 | |
| SCHEMBL14306777 | 0.86 | ADRA1D (0.80) | ADRA1DSLC6A4 | |
| SCHEMBL2488545 | 0.82 | ADRA1D (0.67) | ADRA1DSLC6A4 | |
| SCHEMBL2488547 | 0.82 | ADRA1D (0.67) | ADRA1DSLC6A4 | |
| Hydrochloric Acid SCHEMBL7259157 | 0.82 | ADRA1D (0.90) | ADRA1DSLC6A4 | |
| SCHEMBL11969517 | 0.81 | ADRA1D (0.65) | ADRA1DSLC6A4 | |
| SCHEMBL11969519 | 0.81 | ADRA1D (0.65) | ADRA1DSLC6A4 | |
| SCHEMBL6383575 | 0.81 | ADRA1D (0.72) | ADRA1DSLC6A4DRD2 | |
| SCHEMBL4468600 | 0.81 | ADRA1D (0.72) | ADRA1DSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079190-A1 | 3-SUBSTITUTED INDOLES AS CHEMOKINE ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-10-10 | — | — | WO | disclosed |