Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 13/20 | 0.43 |
| ▸ | PDE4A | P27815 | 10/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696756 | 0.76 | PDE4B (0.49) | PDE4BPDE4APDE4DPDE4C | |
| SCHEMBL8707894 | 0.76 | PDE4B (0.45) | PDE4BPDE4APDE4DPDE4C | |
| SCHEMBL8707032 | 0.74 | PDE4B (0.45) | PDE4BPDE4APDE4DPDE4C | |
| SCHEMBL7694316 | 0.70 | HTR2C (0.61) | PDE4BPDE4APDE4DPDE4C | |
| SCHEMBL8708075 | 0.70 | SMN1; SMN2 (0.50) | PDE4BPDE4APDE4DPDE4C | |
| SCHEMBL8710395 | 0.70 | PDE4D (0.45) | PDE4BPDE4APDE4DPDE4CPOLB | |
| SCHEMBL1157492 | 0.69 | PDE4A (0.44) | PDE4BPDE4APDE4DPDE4C | |
| SCHEMBL8715714 | 0.69 | PDE4A (0.49) | PDE4BPDE4APDE4DPDE4CPOLB | |
| SCHEMBL7688170 | 0.68 | PDE4B (0.57) | PDE4BPDE4APDE4DPDE4C | |
| SCHEMBL5084709 | 0.67 | CA12 (0.54) | PDE4BPDE4APDE4DPDE4CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |