Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.57 |
| ▸ | PDE4A | P27815 | 14/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.57 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713399 | 0.99 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DNR1H3 | |
| SCHEMBL8707864 | 0.92 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DNR1H3 | |
| SCHEMBL8712873 | 0.91 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DNR1H3 | |
| SCHEMBL6171171 | 0.87 | PDE4B (0.50) | PDE4BPDE4APDE4CPDE4DNR1H3 | |
| SCHEMBL8707692 | 0.86 | NR1H3 (0.53) | PDE4BPDE4APDE4CPDE4DNR1H3 | |
| SCHEMBL7694019 | 0.86 | PDE4A (0.48) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7689616 | 0.84 | NR1H3 (0.71) | NR1H3NR1H2 | |
| SCHEMBL7694219 | 0.84 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8707496 | 0.82 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7694316 | 0.82 | HTR2C (0.61) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081447-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOTHIAZOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |