Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.58 |
| ▸ | AGXT | P21549 | 2/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 7/20 | 0.53 |
| ▸ | HTR2C | P28335 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431834 | 0.87 | IDO1 (0.57) | IDO1AGXTDAOHTR2AHTR2C | |
| SCHEMBL1116576 | 0.87 | IDO1 (0.57) | IDO1AGXTDAOHTR2AHTR2C | |
| SCHEMBL1385782 | 0.87 | IDO1 (0.52) | IDO1AGXTDAOHTR2AHTR2C | |
| SCHEMBL27465879 | 0.87 | DAO (0.47) | IDO1AGXTDAOHTR2AHTR2C | |
| SCHEMBL13376628 | 0.85 | IDO1 (0.50) | IDO1AGXTDAOHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL2209462 | 0.85 | IDO1 (0.59) | IDO1AGXTDAOHTR2AHTR2C | |
| SCHEMBL1121847 | 0.85 | IDO1 (0.50) | IDO1AGXTDAOHTR2AHTR2C | |
| SCHEMBL17552660 | 0.85 | IDO1 (0.50) | IDO1AGXTDAOHTR2AHTR2C | |
| SCHEMBL7337981 | 0.85 | IDO1 (0.50) | IDO1AGXTDAOHTR2AHTR2C | |
| SCHEMBL3124398 | 0.85 | IDO1 (0.50) | IDO1AGXTDAOHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342504-B1 | PEPTIDES AS ANTITHROMBINS AND ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2002-01-29 | — | — | US | disclosed |