SCHEMBL27465879

SCHEMBL27465879

Cc1ccc(CCc2ccc(F)cc2F)c(F)c1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.47
IDO1 P14902 2/20 0.47
AGXT P21549 2/20 0.47
NFE2L2 Q16236 2/20 0.46
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45
ACHE P22303 2/20 0.42
KDM4E B2RXH2 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAOB P27338 1/20 0.41
TAAR1 Q96RJ0 1/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
NR3C2 P08235 1/20 0.38
MAPK14 Q16539 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18590775 0.91 TAAR1 (0.45) DAONFE2L2HTR2AACHETAAR1
SCHEMBL7700904 0.87 IDO1 (0.58) DAOIDO1AGXTHTR2AHTR2C
SCHEMBL24940563 0.83 TAAR1 (0.44) NFE2L2KDM4ESMN1; SMN2TAAR1
SCHEMBL19335895 0.82 TAAR1 (0.48) DAONFE2L2HTR2AHTR2CTAAR1
SCHEMBL20097441 0.82 TAAR1 (0.38) DAONFE2L2HTR2ATAAR1
SCHEMBL17769201 0.81 TAAR1 (0.61) HTR2AKDM4ETAAR1
SCHEMBL9921236 0.81 TAAR1 (0.41) NFE2L2HTR2AACHETAAR1
SCHEMBL18772818 0.80 TAAR1 (0.41) DAONFE2L2HTR2ATAAR1SLC6A4
SCHEMBL21387161 0.80 TAAR1 (0.41) NFE2L2ACHETAAR1
SCHEMBL22248863 0.79 TAAR1 (0.39) IDO1NFE2L2HTR2AACHETAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024142556-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND PATTERN FORMATION METHOD JSR株式会社 2024-07-04 WO disclosed