Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258103 | 0.83 | ESR1 (0.51) | SRCESR1ESR2CYP2D6KMT2A | |
| SCHEMBL10688255 | 0.78 | KMT2A (0.38) | SRCESR1ESR2KMT2ATSHR | |
| SCHEMBL130469 | 0.76 | PDCD1 (0.47) | KMT2ATP53TSHRLMNAALDH1A1 | |
| SCHEMBL28088354 | 0.75 | TSHR (0.57) | ESR1ESR2KMT2ATP53TSHR | |
| SCHEMBL28387238 | 0.73 | CYP2D6 (0.44) | SRCESR1ESR2CYP2D6KMT2A | |
| SCHEMBL28387237 | 0.73 | CYP2D6 (0.44) | SRCESR1ESR2CYP2D6KMT2A | |
| SCHEMBL11082448 | 0.71 | ESR1 (0.41) | SRCESR1ESR2CYP2D6KMT2A | |
| SCHEMBL10700173 | 0.71 | TSHR (0.37) | CYP2D6KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL6953946 | 0.71 | MAPT (0.41) | CYP2D6KMT2ATP53TSHRLMNA | |
| SCHEMBL8747402 | 0.71 | TSHR (0.35) | CYP2D6KMT2ATSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057262-A2 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LIMITED (GB) | 2002-07-25 | — | — | WO | claimed |