Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976602 | 1.00 | AGTR2 (1.00) | AGTR2AGTR1 | |
| Potassium SCHEMBL8976441 | 0.99 | AGTR2 (0.98) | AGTR2AGTR1 | |
| SCHEMBL8976768 | 0.99 | AGTR2 (0.98) | AGTR2AGTR1 | |
| SCHEMBL7021272 | 0.95 | AGTR2 (1.00) | AGTR2AGTR1 | |
| SCHEMBL8348232 | 0.94 | AGTR2 (0.90) | AGTR2AGTR1 | |
| SCHEMBL8346714 | 0.93 | AGTR2 (0.87) | AGTR2AGTR1 | |
| SCHEMBL8348141 | 0.93 | AGTR2 (1.00) | AGTR2AGTR1 | |
| SCHEMBL7022990 | 0.93 | AGTR2 (0.89) | AGTR2AGTR1 | |
| Potassium Ion SCHEMBL29486795 | 0.92 | AGTR2 (1.00) | AGTR2AGTR1 | |
| Potassium Ion SCHEMBL8976436 | 0.92 | AGTR2 (1.00) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644188-B1 | Process for the preparation of sulfur derivatives of imidazole and intermediates obtained | AVENTIS PHARMA SA (FR) | 2002-12-04 | — | — | EP | claimed |
| EP-0648763-B1 | Process for the preparation of sulfur derivatives of imidazole and intermediates obtained | AVENTIS PHARMA SA (FR) | 2001-05-09 | — | — | EP | claimed |
| US-5612365-A | CARDIOVASCULAR DISORDERS AND COGNITIVE ACTIVATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5527919-A | Process for the preparation of 1-[(1,1'-biphenyl]-4-YL]-methyl-1H-imidazole-5-carboxylic acids | ROUSSEL UCLAF (FR) | 1996-06-18 | — | — | US | disclosed |
| US-5475004-A | Angiotensin II receptor antagonists for the treatment and prophylaxis of coronary heart disease | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| US-5468764-A | Administering to a mammal an azole derivative | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-21 | — | — | US | disclosed |
| EP-0577025-A2 | Angiotensin-II-receptorantagonist for the treatment and prophylaxis of coronary heart diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-05 | — | — | EP | disclosed |
| EP-0577023-A2 | Angiotensin-II receptor-antagonists for the treatment of arrhythmices | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-05 | — | — | EP | disclosed |