Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711302 | 0.89 | HTR2C (0.44) | HTR2CNPC1RAB9APKMMCHR1 | |
| SCHEMBL7696591 | 0.89 | MCHR1 (0.49) | HTR2CNPC1RAB9APKMMCHR1 | |
| SCHEMBL7698181 | 0.89 | MCHR1 (0.49) | HTR2CNPC1RAB9APKMMCHR1 | |
| SCHEMBL8707222 | 0.89 | MCHR1 (0.45) | HTR2CNPC1RAB9APKMMCHR1 | |
| SCHEMBL7694961 | 0.87 | MCHR1 (0.47) | HTR2CNPC1RAB9APKMMCHR1 | |
| SCHEMBL8710747 | 0.87 | MCHR1 (0.48) | HTR2CMCHR1PDE4APDE4BPDE4C | |
| SCHEMBL7695024 | 0.84 | MCHR1 (0.46) | HTR2CNPC1RAB9AMCHR1SMN1; SMN2 | |
| SCHEMBL8707494 | 0.84 | MCHR1 (0.46) | HTR2CMCHR1PIK3CGSMN1; SMN2TP53 | |
| SCHEMBL8713921 | 0.84 | MCHR1 (0.46) | HTR2CNPC1RAB9AMCHR1PIK3CG | |
| SCHEMBL7692652 | 0.84 | NR1H3 (0.60) | MCHR1KMT2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |