Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707874 | 0.94 | MCHR1 (0.45) | MCHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8713921 | 0.89 | MCHR1 (0.46) | MCHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8708911 | 0.85 | PDE4B (0.41) | MCHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7696591 | 0.85 | MCHR1 (0.49) | MCHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7701165 | 0.84 | HTR2C (0.56) | MCHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7698181 | 0.83 | MCHR1 (0.49) | MCHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7695024 | 0.82 | MCHR1 (0.46) | MCHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8711752 | 0.81 | MCHR1 (0.47) | MCHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7694961 | 0.80 | MCHR1 (0.47) | MCHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7699175 | 0.80 | MCHR1 (0.45) | MCHR1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |