Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696449 | 0.98 | HTT (0.57) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL8668943 | 0.85 | KMT2A (0.54) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL6790329 | 0.85 | SMN1; SMN2 (0.59) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL8608392 | 0.85 | KMT2A (0.54) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL5849107 | 0.83 | KMT2A (0.53) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL2763578 | 0.83 | NPC1 (0.55) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL10480817 | 0.83 | MAPT (0.59) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL3756708 | 0.79 | KMT2A (0.41) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL5860879 | 0.79 | CYP2D6 (0.61) | MAPTKCNQ2HTTSMN1; SMN2NPC1 | |
| SCHEMBL5918694 | 0.78 | KMT2A (0.62) | KMT2AMEN1L3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076965-A1 | NON PEPTIDE MIMETICS BASED ON THE ACTIVE SEQUENCE S42FLLR46 OF THE THROMBIN RECEPTOR FOR THE TREATMENT OF THROMBOSIS AND CANCER | MATSOUKAS JOHN (GR) | 2002-10-03 | — | — | WO | disclosed |