Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693763 | 0.93 | KDM4E (0.58) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL7699621 | 0.91 | MAPT (0.59) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL7699146 | 0.90 | MAPT (0.57) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL7698787 | 0.89 | KDM4E (0.58) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL7696422 | 0.89 | MAPT (0.64) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL7698000 | 0.88 | KDM4E (0.65) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL7695925 | 0.88 | MAPT (0.63) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL7699245 | 0.87 | KDM4E (0.52) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL7698234 | 0.86 | MAPT (0.61) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL7703233 | 0.82 | KDM4E (0.73) | MAPTALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |