Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | STAT3 | P40763 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703233 | 0.91 | KDM4E (0.73) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL7694070 | 0.91 | KDM4E (0.73) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL7695082 | 0.89 | MAPT (0.50) | KDM4EGAASTAT3MAPTMEN1 | |
| SCHEMBL7696428 | 0.89 | STAT3 (0.55) | KDM4EGAASTAT3MAPTMEN1 | |
| SCHEMBL7701387 | 0.88 | MAPT (0.69) | KDM4EGAASTAT3MAPTMEN1 | |
| SCHEMBL7703322 | 0.88 | KDM4E (0.72) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL7698787 | 0.86 | KDM4E (0.58) | KDM4EGAASTAT3MAPTKMT2A | |
| SCHEMBL7704976 | 0.86 | MAPT (0.61) | KDM4EGAASTAT3MAPTMEN1 | |
| SCHEMBL7699293 | 0.86 | KDM4E (0.53) | KDM4EGAASTAT3MAPTMEN1 | |
| SCHEMBL7699119 | 0.86 | KDM4E (0.50) | KDM4EGAASTAT3MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |