Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091992 | 0.84 | MEN1 (0.60) | MEN1KMT2ATDP1ALDH1A1TP53 | |
| SCHEMBL7094384 | 0.84 | MEN1 (0.60) | MEN1KMT2ATDP1ALDH1A1TP53 | |
| SCHEMBL7091971 | 0.83 | MEN1 (0.59) | MEN1KMT2ATDP1ALDH1A1TP53 | |
| SCHEMBL7092621 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2ATDP1ALDH1A1TP53 | |
| SCHEMBL7092618 | 0.81 | MEN1 (0.43) | MEN1KMT2ATDP1ALDH1A1TP53 | |
| SCHEMBL7094997 | 0.79 | ALDH1A1 (0.60) | MEN1KMT2ATDP1ALDH1A1TP53 | |
| SCHEMBL7093767 | 0.79 | ALDH1A1 (0.60) | MEN1KMT2ATDP1ALDH1A1TP53 | |
| SCHEMBL7094998 | 0.77 | ALDH1A1 (0.54) | MEN1KMT2ATDP1ALDH1A1TP53 | |
| SCHEMBL7695325 | 0.77 | ALDH1A1 (0.54) | MEN1KMT2ATDP1ALDH1A1TP53 | |
| SCHEMBL7095297 | 0.76 | MEN1 (0.48) | MEN1KMT2ATDP1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |