Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.48 |
| ▸ | DRD4 | P21917 | 4/20 | 0.48 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095533 | 0.78 | DRD4 (0.56) | GRM2DRD4ALDH1A2ALDH1A1ALDH2 | |
| SCHEMBL6095488 | 0.77 | GRM2 (0.50) | GRM2DRD4ALDH1A2ALDH1A1ALDH2 | |
| SCHEMBL15748175 | 0.71 | SIGMAR1 (0.58) | DRD2OPRM1DRD3ABCB11HTR1A | |
| SCHEMBL15748232 | 0.69 | SIGMAR1 (0.59) | DRD2OPRM1DRD3ABCB11HTR1A | |
| SCHEMBL17471515 | 0.69 | DRD3 (0.56) | GRM2DRD4ALDH1A1DRD2TP53 | |
| SCHEMBL6095407 | 0.67 | DRD4 (0.64) | GRM2DRD4DRD2MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7695313 | 0.67 | KDM4E (0.57) | ALDH1A1DRD2TP53KDM4EDRD3 | |
| SCHEMBL11925196 | 0.67 | DRD3 (0.54) | GRM2DRD4ALDH1A1DRD2TP53 | |
| SCHEMBL6864697 | 0.67 | SIGMAR1 (0.76) | DRD4ALDH1A1DRD2TP53KDM4E | |
| SCHEMBL7859184 | 0.66 | PHGDH (0.58) | GRM2DRD4ALDH1A1DRD2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002092575-A1 | BENZIMIDAZOLE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS, INC. (US) | 2002-11-21 | — | — | WO | disclosed |