SCHEMBL7701762

SCHEMBL7701762

COC(=O)CC(O)C(=O)OC.O=C(O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 2/20 0.53
ALDH1A1 P00352 5/20 0.47
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALOX15 P16050 1/20 0.45
LTA4H P09960 1/20 0.43
KMT2A Q03164 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A3 Q01959 1/20 0.42
TRPM8 Q7Z2W7 1/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
MAOB P27338 1/20 0.42
KYNU Q16719 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SLC15A1 P46059 1/20 0.41
REN P00797 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8300048 0.89 ALDH1A1 (0.54) ABCB1ALDH1A1MAPK1L3MBTL1ALOX15
SCHEMBL9781688 0.89 ABCB1 (0.56) ABCB1ALDH1A1MAPK1L3MBTL1ALOX15
SCHEMBL9781686 0.89 ALDH1A1 (0.54) ABCB1ALDH1A1MAPK1L3MBTL1ALOX15
SCHEMBL29714837 0.82 ABCB1 (0.44) ABCB1ALDH1A1L3MBTL1LTA4HKMT2A
Mandelic Acid, Methyl Ester SCHEMBL7704691 0.79 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1LTA4HKMT2A
SCHEMBL673677 0.78 ALDH1A1 (0.59) ABCB1ALDH1A1MAPK1L3MBTL1LTA4H
SCHEMBL16399030 0.78 ALDH1A1 (0.59) ABCB1ALDH1A1MAPK1L3MBTL1LTA4H
SCHEMBL27981610 0.77 ABCB1 (0.53) ABCB1ALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL1691025 0.77 TSHR (0.43) ABCB1KMT2ARAB9A
SCHEMBL30001820 0.77 ALDH1A1 (0.68) ALDH1A1MAPK1L3MBTL1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6469193-B1 THREE COMPONENT COUPLINGS OF ALIPHATIC ALCOHOLS, ALKYL HALIDES AND CARBON DIOXIDE IN THE PRESENCE OF CESIUM CARBONATE AND TETRABUTYLAMMONIUM IODIDE UNIVERSITY OF SOUTH FLORIDA 2002-10-22 US disclosed
WO-2000050376-A9 EFFICIENT SYNTHESIS OF ALKYL CARBONATES UNIV SOUTH FLORIDA (US) 2001-10-11 WO disclosed
WO-2000050376-A2 EFFICIENT SYNTHESIS OF ALKYL CARBONATES UNIVERSITY OF SOUTH FLORIDA (US) 2000-08-31 WO disclosed