SCHEMBL7701890

SCHEMBL7701890

Cc1cc2c(cc1C)C(O)C(C)C2

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 1/20 0.33
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30082461 0.78 MEN1 (0.31) MEN1MAPTKMT2ANPSR1
SCHEMBL30666589 0.78 MEN1 (0.31) MEN1MAPTKMT2ANPSR1
SCHEMBL30082451 0.76 MEN1 (0.30) MEN1MAPTKMT2ANPSR1
SCHEMBL27145561 0.76 TRPM5 (0.41) KMT2A
SCHEMBL27146256 0.76 TRPM5 (0.41) KMT2A
SCHEMBL10022871 0.76 SLC22A12 (0.32) SLC22A12
SCHEMBL21436027 0.76 SLC22A12 (0.32) SLC22A12MEN1MAPTKMT2AALDH1A1
SCHEMBL30082449 0.76 MEN1 (0.30) MEN1MAPTKMT2ANPSR1
SCHEMBL3660249 0.72 ATM (0.33)
SCHEMBL20615156 0.71 CA1 (0.42) SLC22A12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE37573-E1 Process for the preparation of an olefin polymer using metallocenes containing specifically substituted indenyl ligands BASELL POLYOLEFIN GMBH (DE) 2002-03-05 US disclosed
US-5869584-A Process for the preparation of an olefin polymer using metallocenes containing specifically substituted indenyl ligands TARGOR GMBH (DE) 1999-02-09 US disclosed
EP-0582194-B1 Process for the preparation of polymers using metallocenes with specifically substituted indenyl ligands TARGOR GMBH (DE) 1998-05-06 EP disclosed
US-5455365-A Metallocene compound containing substituted indenyl ligand and transition metal element from groups IVb, Vb, or VIb; addition polymerization with aluminoxane cocatalyst HOECHST AG (DE) 1995-10-03 US disclosed
EP-0582194-A1 Process for the preparation of polymers using metallocenes with specifically substituted indenyl ligands HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-09 EP disclosed