⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16860004 | 0.82 | — | — | |
| SCHEMBL4647958 | 0.71 | — | — | |
| SCHEMBL126523 | 0.71 | — | — | |
| SCHEMBL25375775 | 0.67 | — | — | |
| SCHEMBL4645019 | 0.61 | — | — | |
| SCHEMBL3630272 | 0.59 | — | — | |
| SCHEMBL1112353 | 0.58 | — | — | |
| SCHEMBL21859 | 0.58 | — | — | |
| SCHEMBL11529479 | 0.58 | — | — | |
| SCHEMBL28754303 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919484-B1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | SHANDONG XUANZHU PHARMA CO LTD (CN) | 2023-05-24 | — | — | EP | disclosed |
| CN-115707708-A | Wee1 kinase inhibitors | 轩竹生物科技股份有限公司 | 2023-02-21 | — | — | CN | disclosed |
| CN-115197221-A | Dihydropyrazolopyrimidinone macrocyclic derivatives and application thereof | 轩竹生物科技股份有限公司 | 2022-10-18 | — | — | CN | disclosed |
| EP-3919484-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | Shandong Xuanzhu Pharma Co., Ltd. (CN) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020156445-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | 山东轩竹医药科技有限公司 | 2020-08-06 | — | — | WO | disclosed |
| EP-3089584-A1 | AGRICULTURAL PESTICIDE COMPOSITIONS | Rhodia Operations (FR) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015103192-A1 | AGRICULTURAL PESTICIDE COMPOSITIONS | RHODIA OPERATIONS (FR) | 2015-07-09 | — | — | WO | disclosed |
| US-20150181862-A1 | AGRICULTURAL PESTICIDE COMPOSITIONS | RHODIA OPERATIONS (FR) | 2015-07-02 | — | — | US | disclosed |
| EP-0900218-B1 | HETEROCYCLIC COMPOUNDS | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-0900218-A4 | HETEROCYCLIC COMPOUNDS | LILLY CO ELI (US) | 2001-05-23 | — | — | EP | disclosed |
| EP-0776897-A1 | Heterocyclic compounds and their use | ELI LILLY AND COMPANY (US) | 1997-06-04 | — | — | EP | disclosed |
| WO-1997017962-A1 | METHOD FOR TREATING ANXIETY | ELI LILLY AND COMPANY (US) | 1997-05-22 | — | — | WO | disclosed |
| EP-0774256-A1 | Use of azacyclic or azabicyclic thiadiazole compounds for treating anxiety | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |
| EP-0773027-A1 | Use of azacyclic or azabicyclic pyrazine compounds for treating anxiety | ELI LILLY AND COMPANY (US) | 1997-05-14 | — | — | EP | disclosed |
| EP-0773021-A1 | Use of azacyclic or azabicyclic oxadiazole compounds for treating anxiety | ELI LILLY AND COMPANY (US) | 1997-05-14 | — | — | EP | disclosed |
| US-5605908-A | TREATING DISEASES OF CENTRAL NERVOUS SYSTEM CAUSED BY MALFUNCTIONING OF MUSCARINIC CHOLINERGIC SYSTEM | ELI LILLY AND COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| WO-1996038431-A1 | PROCESS FOR MAKING HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 1996-12-05 | — | — | WO | disclosed |
| EP-0745601-A1 | Process for preparing 1,2,5-thiadiazole derivatives | ELI LILLY AND COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |
| WO-1996012711-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE | ELI LILLY AND COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |
| EP-0709381-A1 | Heterocyclic compounds and their preparation and use | ELI LILLY AND COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |