Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | UBE2N | P61088 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701075 | 0.91 | MEN1 (0.82) | MEN1KMT2AUBE2NMAPTALDH1A1 | |
| SCHEMBL7694685 | 0.87 | MEN1 (1.00) | MEN1KMT2AUBE2NMAPTALDH1A1 | |
| SCHEMBL7700613 | 0.86 | MAPT (0.62) | MEN1KMT2AUBE2NMAPTTDP1 | |
| SCHEMBL7694832 | 0.83 | MEN1 (0.71) | MEN1KMT2AUBE2NMAPTTDP1 | |
| SCHEMBL7663409 | 0.81 | ALDH1A1 (0.72) | MEN1KMT2AUBE2NMAPTTDP1 | |
| SCHEMBL7539415 | 0.80 | KMT2A (0.67) | MEN1KMT2AUBE2NMAPTTDP1 | |
| SCHEMBL15308654 | 0.79 | MAPT (0.62) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL10040175 | 0.78 | MAPT (0.65) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL25009190 | 0.78 | MAPT (0.77) | MEN1KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL7667933 | 0.78 | ALDH1A1 (0.67) | MEN1KMT2AUBE2NMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |