Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702938 | 0.87 | HDAC1 (0.43) | HTR1AHTR1DHTR1BNPSR1SLC6A2 | |
| SCHEMBL24398904 | 0.80 | NPSR1 (0.39) | NPSR1SLC6A2SLC6A4NPC1RAB9A | |
| SCHEMBL7126896 | 0.78 | AGXT (0.46) | NPSR1SLC6A2SLC6A4NPC1RAB9A | |
| SCHEMBL7701212 | 0.76 | NPC1 (0.47) | NPSR1SLC6A2SLC6A4HDAC1NPC1 | |
| SCHEMBL7697654 | 0.76 | NPC1 (0.47) | NPSR1SLC6A2SLC6A4HDAC1NPC1 | |
| SCHEMBL7703198 | 0.76 | NPC1 (0.47) | NPSR1SLC6A2SLC6A4HDAC1NPC1 | |
| SCHEMBL7690100 | 0.76 | NPC1 (0.47) | NPSR1SLC6A2SLC6A4HDAC1NPC1 | |
| SCHEMBL7689586 | 0.76 | NPC1 (0.47) | NPSR1SLC6A2SLC6A4HDAC1NPC1 | |
| SCHEMBL12370647 | 0.76 | NPC1 (0.47) | NPSR1SLC6A2SLC6A4HDAC1NPC1 | |
| SCHEMBL7689434 | 0.76 | NPC1 (0.38) | HTR1AHTR1DHTR1BNPSR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024619-A1 | AMINE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 2002-03-28 | — | — | WO | disclosed |