Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 4/20 | 0.35 |
| ▸ | F3 | P13726 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 4/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | STAT6 | P42226 | 3/20 | 0.34 |
| ▸ | STAT5A | P42229 | 2/20 | 0.34 |
| ▸ | STAT5B | P51692 | 2/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439829 | 0.84 | F2 (0.36) | F7F3F2F10F11 | |
| SCHEMBL6439832 | 0.84 | F2 (0.36) | F7F3F2F10F11 | |
| SCHEMBL7699519 | 0.84 | F2 (0.36) | F7F3F2F10F11 | |
| SCHEMBL6436664 | 0.81 | F2 (0.41) | F7F3F2F10F11 | |
| SCHEMBL6436662 | 0.81 | F2 (0.41) | F7F3F2F10F11 | |
| SCHEMBL7705499 | 0.77 | F2 (0.36) | F2F11STAT6STAT5ASTAT5B | |
| SCHEMBL6438912 | 0.72 | KCNH2 (0.45) | F7F3F2F10F11 | |
| SCHEMBL6438909 | 0.72 | KCNH2 (0.45) | F7F3F2F10F11 | |
| SCHEMBL6436257 | 0.70 | F2 (0.47) | F7F2F10F11PRSS1 | |
| SCHEMBL6436260 | 0.70 | F2 (0.47) | F7F2F10F11PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444672-B1 | ORAL BIOVAILABILITY; INHIBITORS OF THROMBIN AND/OR FACTOR XA; SERINE PROTEASE INHIBITOR | AKZO NOBEL N.V. (NL) | 2002-09-03 | — | — | US | disclosed |