Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | F11 | P03951 | 7/20 | 0.32 |
| ▸ | STAT6 | P42226 | 2/20 | 0.32 |
| ▸ | STAT5A | P42229 | 2/20 | 0.32 |
| ▸ | STAT5B | P51692 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718116 | 0.82 | F2 (0.44) | F2PRSS1PLATF11 | |
| SCHEMBL6436747 | 0.82 | F2 (0.44) | F2PRSS1PLATF11 | |
| SCHEMBL7969522 | 0.80 | F2 (0.40) | F2PRSS1PLATF11STAT6 | |
| SCHEMBL7702444 | 0.77 | F7 (0.35) | F2PRSS1F11STAT6STAT5A | |
| SCHEMBL6436257 | 0.74 | F2 (0.47) | F2PRSS1PLATF11 | |
| SCHEMBL6436260 | 0.74 | F2 (0.47) | F2PRSS1PLATF11 | |
| SCHEMBL6436637 | 0.73 | F11 (0.56) | F2PRSS1PLATF11 | |
| SCHEMBL6436645 | 0.73 | F11 (0.56) | F2PRSS1PLATF11 | |
| SCHEMBL6436284 | 0.73 | F2 (0.44) | F2PRSS1PLATF11 | |
| SCHEMBL6436292 | 0.73 | F2 (0.44) | F2PRSS1PLATF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444672-B1 | ORAL BIOVAILABILITY; INHIBITORS OF THROMBIN AND/OR FACTOR XA; SERINE PROTEASE INHIBITOR | AKZO NOBEL N.V. (NL) | 2002-09-03 | — | — | US | disclosed |