Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 13/20 | 0.64 |
| ▸ | CCNE2 | O96020 | 11/20 | 0.64 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.64 |
| ▸ | CDK1 | P06493 | 9/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.61 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.61 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.61 |
| ▸ | PDE5A | O76074 | 1/20 | 0.61 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.61 |
| ▸ | CDK7 | P50613 | 1/20 | 0.61 |
| ▸ | CDK9 | P50750 | 1/20 | 0.61 |
| ▸ | CCNH | P51946 | 1/20 | 0.61 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.61 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.52 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272902 | 0.85 | CCNE2 (0.84) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL14071580 | 0.79 | CDK2 (0.85) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL3680752 | 0.78 | CCNE1 (0.82) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL6143053 | 0.78 | CDK2 (1.00) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL6016549 | 0.78 | CDK2 (0.74) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL6016512 | 0.78 | CDK1 (0.78) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL6016614 | 0.77 | CDK1 (0.81) | CDK2CCNE1CDK1CCNB1CDK5 | |
| SCHEMBL6016617 | 0.77 | CDK1 (0.81) | CDK2CCNE1CDK1CCNB1CDK5 | |
| SCHEMBL6016673 | 0.77 | CDK2 (0.71) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL2907920 | 0.77 | CDK1 (0.81) | CDK2CCNE2CCNE1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244668-A1 | PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 2002-10-02 | — | — | EP | claimed |
| WO-2001049688-A1 | PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 2001-07-12 | — | — | WO | claimed |