Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 13/20 | 0.78 |
| ▸ | CCNB2 | O95067 | 12/20 | 0.78 |
| ▸ | CCNB1 | P14635 | 12/20 | 0.78 |
| ▸ | CCNB3 | Q8WWL7 | 12/20 | 0.78 |
| ▸ | CDK2 | P24941 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.64 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.64 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.64 |
| ▸ | CDK7 | P50613 | 1/20 | 0.64 |
| ▸ | CCNH | P51946 | 1/20 | 0.64 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.64 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.55 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.55 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754120 | 0.82 | CDK1 (1.00) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL30539284 | 0.82 | CDK1 (1.00) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL7041292 | 0.80 | CDK1 (1.00) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6016549 | 0.80 | CDK2 (0.74) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6016673 | 0.79 | CDK2 (0.71) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL7146120 | 0.79 | CCNB2 (0.52) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL22789735 | 0.78 | CDK2 (1.00) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6016359 | 0.78 | CCNB2 (0.54) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6016614 | 0.78 | CDK1 (0.81) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6016617 | 0.78 | CDK1 (0.81) | CDK1CCNB2CCNB1CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244668-B1 | PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | UNIVERSITAIRE INSTELLING ANTWE (BE) | 2006-04-05 | — | — | EP | claimed |
| US-20030187261-A1 | Purine derivatives, process for their preparation and use thereof | USTAV EXPERIMANTALNI BOTANIKY AKADEMIE VED CESKE REPUBLIKY (CZ) | 2003-10-02 | — | — | US | claimed |
| US-20030187261-A1 | Purine derivatives, process for their preparation and use thereof | USTAV EXPERIMANTALNI BOTANIKY AKADEMIE VED CESKE REPUBLIKY (CZ) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187261-A1 | Purine derivatives, process for their preparation and use thereof | DCK, DTYMK, CCNK | CDK1 7/4885CCNB2 127/4885CCNB1 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.