SCHEMBL7702472

SCHEMBL7702472

Clc1nc2cncnc2[nH]1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RPS6KA5 O75582 1/20 0.35
EGFR P00533 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312294 0.77 EGFR (0.38) EGFR
SCHEMBL9572676 0.75 EGFR (0.33) EGFR
SCHEMBL2011130 0.75 EGFR (0.33) EGFR
SCHEMBL2141779 0.75 EGFR (0.34) EGFR
SCHEMBL1586125 0.75 EGFR (0.33) EGFR
SCHEMBL9652879 0.75 EGFR (0.33) EGFR
SCHEMBL1021063 0.75 EGFR (0.33) EGFR
SCHEMBL1963573 0.75 ADORA2A (0.36) EGFR
SCHEMBL7948683 0.75 EGFR (0.33) EGFR
SCHEMBL277594 0.75 EGFR (0.33) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017021983-A1 PARTICULATE DELIVERY SYSTEMS RUBICON RESEARCH PRIVATE LIMITED (IN) 2017-02-09 WO disclosed
EP-1244668-A1 PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF UNIVERSITAIRE INSTELLING ANTWERPEN (BE) 2002-10-02 EP disclosed
WO-2001049688-A1 PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF UNIVERSITAIRE INSTELLING ANTWERPEN (BE) 2001-07-12 WO disclosed
EP-0479640-A2 Novel phosphonate derivatives of certain nucleosides MERRELL DOW PHARMACEUTICALS INC. (US) 1992-04-08 EP disclosed
EP-0477454-A1 Novel phosphonate derivatives of certain nucleosides MERRELL DOW PHARMACEUTICALS INC. (US) 1992-04-01 EP disclosed
CN-1036578-A NOVEL FLUOROPHOSPHONATE NUCLEOTIDE DERIVATIVES MERRELL DOW PHARMA (US) 1989-10-25 CN disclosed
EP-0335770-A2 Novel fluorophosphonate nucleotide derivatives MERRELL PHARMACEUTICALS INC. (US) 1989-10-04 EP disclosed