SCHEMBL1021063

SCHEMBL1021063

Oc1nc2cncnc2[nH]1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGFR P00533 5/20 0.33
PIK3CG P48736 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312294 0.77 EGFR (0.38) EGFR
SCHEMBL2011130 0.75 EGFR (0.33) EGFR
SCHEMBL1963573 0.75 ADORA2A (0.36) EGFR
SCHEMBL277594 0.75 EGFR (0.33) EGFR
SCHEMBL1586125 0.75 EGFR (0.33) EGFR
SCHEMBL9652879 0.75 EGFR (0.33) EGFR
SCHEMBL7948683 0.75 EGFR (0.33) EGFR
SCHEMBL2141779 0.75 EGFR (0.34) EGFR
SCHEMBL4957388 0.75 KDM4E (0.38) EGFR
SCHEMBL788917 0.73 PKN1 (0.33) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113416522-A Low-conductivity anti-freezing cooling liquid for new energy power battery and preparation method thereof 上海科鸿能源发展有限公司 2021-09-21 CN claimed
WO-2017062966-A1 ANTIBODIES SPECIFIC FOR 4,6-DIAMINO-5-(FORMYULAMINO) PYRIMIDINE AND USES THEREOF FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2017-04-13 WO claimed
US-20050026862-A1 Cosmetic or dermatological preparation BEIERSDORF AG 2005-02-03 US claimed
EP-1282680-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2003-02-12 EP claimed
US-6503413-B2 Polyalkylene polysiloxane, buffering agent, aqueous carrier THE PROCTER & GAMBLE COMPANY 2003-01-07 US claimed
EP-1255806-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2002-11-13 EP claimed
US-20020011584-A1 Stable, aqueous compositions for treating surfaces, especially fabrics THE PROCTOR & GAMBLE COMPANY 2002-01-31 US claimed
US-20020010154-A1 Compositions comprising cyclodextrin THE PROCTER & GAMBLE COMPANY 2002-01-24 US claimed
WO-2001088076-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2001-11-22 WO claimed
WO-2001060961-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2001-08-23 WO claimed
EP-4652271-A1 BASE EDITING-MEDIATED READTHROUGH OF PREMATURE TERMINATION CODONS (BERT) The Broad Institute, Inc. (US) 2025-11-26 EP disclosed
US-20250339559-A1 BASE EDITING-MEDIATED READTHROUGH OF PREMATURE TERMINATION CODONS (BERT) THE BROAD INSTITUTE, INC. (US) 2025-11-06 US disclosed
EP-3252172-B1 FAST HYBRIDIZATION FOR NEXT GENERATION SEQUENCING TARGET ENRICHMENT AGILENT TECHNOLOGIES INC (US) 2024-09-11 EP disclosed
CN-118496292-A Compounds and methods for reducing SNCA expression IONIS制药公司 2024-08-16 CN disclosed
WO-2024155745-A1 BASE EDITING-MEDIATED READTHROUGH OF PREMATURE TERMINATION CODONS (BERT) THE BROAD INSTITUTE, INC. (US) 2024-07-25 WO disclosed
WO-2001060961-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2001-08-23 WO disclosed
EP-0479640-A2 Novel phosphonate derivatives of certain nucleosides MERRELL DOW PHARMACEUTICALS INC. (US) 1992-04-08 EP disclosed
EP-0477454-A1 Novel phosphonate derivatives of certain nucleosides MERRELL DOW PHARMACEUTICALS INC. (US) 1992-04-01 EP disclosed
EP-0335770-A2 Novel fluorophosphonate nucleotide derivatives MERRELL PHARMACEUTICALS INC. (US) 1989-10-04 EP disclosed
US-4454133-A REACTION PRODUCT OF GLUTARALDEHYDE AND CYCLIC AMIDE OR IMIDE SUTTON LABORATORIES, INC. (US) 1984-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010154-A1 Compositions comprising cyclodextrin FFAR4, FRG1, FGB EGFR 568/4885PIK3CG 349/4885
US-20050026862-A1 Cosmetic or dermatological preparation OGG1, UNG, MPG EGFR 3085/4885PIK3CG 2599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.