Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.47 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702507 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BITGAVF2TMPRSS6 | |
| SCHEMBL7698702 | 0.93 | ITGB3 (0.40) | ITGB3ITGA2BF2TMPRSS6 | |
| SCHEMBL7698698 | 0.93 | ITGB3 (0.40) | ITGB3ITGA2BF2TMPRSS6 | |
| SCHEMBL7697136 | 0.92 | ITGB3 (0.45) | ITGB3ITGA2BITGAVF2TMPRSS6 | |
| SCHEMBL7697141 | 0.92 | ITGB3 (0.45) | ITGB3ITGA2BITGAVF2TMPRSS6 | |
| SCHEMBL7702509 | 0.87 | ITGB3 (0.48) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL7702515 | 0.87 | ITGB3 (0.48) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL7702564 | 0.85 | MAPT (0.41) | ITGB3ITGA2BF2TMPRSS6 | |
| SCHEMBL7702556 | 0.85 | MAPT (0.41) | ITGB3ITGA2BF2TMPRSS6 | |
| SCHEMBL7748714 | 0.81 | ITGB3 (0.63) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348504-B1 | COMPOUNDS WITH AMIDINE OR GUANIDINE GROUPS AND CARBOXY OR ESTER GROUPS THROMBOLYTICS AND/OR FOR THE TREATMENT OF THROMBOEMBOLIC DISORDERS. | DUPONT PHARMACEUTICALS COMPANY | 2002-02-19 | — | — | US | claimed |
| US-6348504-B1 | COMPOUNDS WITH AMIDINE OR GUANIDINE GROUPS AND CARBOXY OR ESTER GROUPS THROMBOLYTICS AND/OR FOR THE TREATMENT OF THROMBOEMBOLIC DISORDERS. | DUPONT PHARMACEUTICALS COMPANY | 2002-02-19 | — | — | US | disclosed |