Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702607 | 1.00 | KDM4E (0.34) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL3367041 | 0.77 | MAOA (0.51) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL3367045 | 0.77 | MAOA (0.51) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL3366821 | 0.64 | MAOA (0.49) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL3366827 | 0.64 | MAOA (0.49) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL6753614 | 0.59 | KCNH2 (0.43) | KDM4EMAPTKMT2AL3MBTL1MAOA | |
| SCHEMBL6753613 | 0.59 | KCNH2 (0.43) | KDM4EMAPTKMT2AL3MBTL1MAOA | |
| SCHEMBL3367097 | 0.58 | MAOA (0.62) | KDM4EMAPTKMT2AL3MBTL1ADRA2A | |
| SCHEMBL3367085 | 0.58 | MAOA (0.62) | KDM4EMAPTKMT2AL3MBTL1ADRA2A | |
| SCHEMBL28506584 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002036588-A2 | REVERSED AMIDINES AND METHODS OF USING FOR TREATING, PREVENTING, OR INHIBITING LEISHMANIASIS | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (US) | 2002-05-10 | — | — | WO | disclosed |