Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457464 | 0.82 | GRIN2D (0.37) | ALOX5AP | |
| Hydrochloric Acid SCHEMBL9457536 | 0.80 | GRIN2D (0.36) | — | |
| SCHEMBL9913257 | 0.78 | GRIN2D (0.35) | KDM1A | |
| SCHEMBL9457622 | 0.75 | GRIN2D (0.32) | — | |
| SCHEMBL830029 | 0.74 | — | — | |
| SCHEMBL19144766 | 0.74 | — | — | |
| Water SCHEMBL9458163 | 0.74 | GRIN2D (0.31) | — | |
| SCHEMBL152170 | 0.73 | ALOX5AP (0.37) | ALOX5APHSD11B1 | |
| SCHEMBL900016 | 0.71 | ALOX5AP (0.39) | ALOX5APHSD11B1 | |
| SCHEMBL3687706 | 0.70 | ALOX5AP (0.35) | ALOX5APHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047583-A1 | TRICYCLIC PYRAZOLE DERIVATIVE AND PREPARATION THEREOF | 四川海思科制药有限公司 | 2021-03-18 | — | — | WO | disclosed |
| US-6353006-B1 | TREATMENT OF BONE DISORDERS, OSTEOPOROSIS AND HEALING AGENT | BAYER CORPORATION | 2002-03-05 | — | — | US | disclosed |
| CN-1337955-A | Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents | AMERICAN BAYER CORP (US) | 2002-02-27 | — | — | CN | disclosed |
| EP-1144396-A2 | SUBSTITUTED 2-ARYLIMINO HETEROCYCLES AND COMPOSITIONS CONTAINING THEM, FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | Bayer Corporation (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042031-A2 | SUBSTITUTED 2-ARYLIMINO HETEROCYCLES AND COMPOSITIONS CONTAINING THEM, FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | BAYER CORPORATION (US) | 2000-07-20 | — | — | WO | disclosed |