Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696673 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL7697083 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL23076447 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL7669614 | 0.77 | MAPT (0.82) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL7701075 | 0.77 | MEN1 (0.82) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL25009358 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL7697087 | 0.74 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL3028204 | 0.73 | MAPT (0.77) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL25011042 | 0.73 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL7699821 | 0.73 | ALDH1A1 (0.80) | ALDH1A1MEN1KMT2AMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |