Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.61 |
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | SDHA | P31040 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CALML3 | P27482 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702676 | 1.00 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6396947 | 0.94 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7711301 | 0.94 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6398288 | 0.94 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6401622 | 0.92 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6401626 | 0.92 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL4875763 | 0.92 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL14197121 | 0.92 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6398365 | 0.88 | MAOA (0.54) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6398362 | 0.88 | MAOA (0.54) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166056-A | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | PHARMACIA (US) | 2000-12-26 | — | — | US | claimed |
| US-6358942-B1 | MICROBIOCIDES AND BACTERICIDES FOR TREATING GRAMPOSITIVE, BACTEROIDES, CLOSTRIDIUM, MYCOBACTERIUM, STAPHYLOCOCCUS AND STREPTOCOCCUS INFECTIONS | PHARMACIA & UPJOHN COMPANY | 2002-03-19 | — | — | US | disclosed |
| US-6166056-A | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | PHARMACIA (US) | 2000-12-26 | — | — | US | disclosed |
| US-6043266-A | MICROBIOCIDES TREATING GRAM-POSITIVE BACTERIA INFECTIONS AND PERSONS WITH AIDS | PHARMACIA & UPJOHN COMPANY (US) | 2000-03-28 | — | — | US | disclosed |