SCHEMBL7702797

SCHEMBL7702797

C=CCCCCCCCCOC(=O)CC(=O)OCCCCCCCCC=C

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
LMNA P02545 2/20 0.55
LPAR3 Q9UBY5 2/20 0.50
LPAR2 Q9HBW0 1/20 0.50
CYP3A4 P08684 3/20 0.48
TSHR P16473 3/20 0.48
MAPT P10636 3/20 0.47
ABCC4 O15439 1/20 0.47
FAAH O00519 2/20 0.46
HTT P42858 1/20 0.41
NAAA Q02083 1/20 0.41
USP2 O75604 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
RECQL P46063 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32674552 1.00 ALDH1A1 (0.55) ALDH1A1LMNALPAR3LPAR2CYP3A4
SCHEMBL9358833 0.91 ALDH1A1 (0.48) ALDH1A1LMNALPAR3LPAR2CYP3A4
SCHEMBL28317561 0.89 ALDH1A1 (0.53) ALDH1A1LMNALPAR3LPAR2CYP3A4
SCHEMBL22832872 0.88 ALDH1A1 (0.55) ALDH1A1LMNALPAR3LPAR2CYP3A4
SCHEMBL964671 0.86 ALDH1A1 (0.50) ALDH1A1LMNALPAR3LPAR2CYP3A4
SCHEMBL284812 0.86 ALDH1A1 (0.63) ALDH1A1LMNALPAR3LPAR2CYP3A4
SCHEMBL11322829 0.86 ALDH1A1 (0.63) ALDH1A1LMNALPAR3LPAR2CYP3A4
SCHEMBL11909573 0.86 ALDH1A1 (0.63) ALDH1A1LMNALPAR3LPAR2CYP3A4
SCHEMBL14244897 0.86 ALDH1A1 (0.63) ALDH1A1LMNALPAR3LPAR2CYP3A4
SCHEMBL11337797 0.86 ALDH1A1 (0.63) ALDH1A1LMNALPAR3LPAR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726345-A Process for perfuming textiles FIRMENICH S.A. (CH) 1998-03-10 US claimed
US-5649979-A LAUNDERING IN PRESENCE OF ESTER COMPOUND WHICH RELEASES FRAGRANT ALCOHOL, ALDEHYDE OR KETONE FIRMENICH S.A. (CH) 1997-07-22 US claimed
US-6348618-B1 PREPARING ORGANOLEPTIC OR ANTIMICROBIAL COMPOUNDS BY CONTACTING BETA-KETO ESTER WITH MATERIAL SELECTED FROM BACTERIA, ENZYMES, AND MATERIAL HAVING ACIDIC OR ALKALINE PH, ELEVATING TEMPERATURE, EXPOSING TO LIGHT GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 2002-02-19 US disclosed
US-6222062-B1 USEFUL AS PRECURSORS FOR ORGANOLEPTIC COMPOUNDS, ESPECIALLY FOR FLAVORS, FRAGRANCES AND MASKING AGENTS AND ANTIMICROBIAL COMPOUNDS GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 2001-04-24 US disclosed
EP-1090624-A2 Beta ketoester Givaudan SA (CH) 2001-04-11 EP disclosed
EP-0953562-A1 Beta, gamma-unsaturated delta-keto esters Givaudan Roure (International) S.A. (CH) 1999-11-03 EP disclosed
EP-0911315-A1 Beta-ketoester Givaudan Roure (International) S.A. (CH) 1999-04-28 EP disclosed
US-5726345-A Process for perfuming textiles FIRMENICH S.A. (CH) 1998-03-10 US disclosed
US-5649979-A LAUNDERING IN PRESENCE OF ESTER COMPOUND WHICH RELEASES FRAGRANT ALCOHOL, ALDEHYDE OR KETONE FIRMENICH S.A. (CH) 1997-07-22 US disclosed