Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702893 | 1.00 | PRCP (0.52) | PRCPGAARECQLGID4TSHR | |
| SCHEMBL7699667 | 0.80 | PRCP (0.64) | PRCPGAARECQLGID4TSHR | |
| Urea SCHEMBL28007088 | 0.78 | PRCP (0.81) | PRCPGAARECQLGID4TSHR | |
| Carbamic Acid SCHEMBL9226170 | 0.78 | PRCP (0.81) | PRCPGAARECQLGID4TSHR | |
| SCHEMBL7699909 | 0.77 | PRCP (0.66) | PRCPGAARECQLGID4TSHR | |
| SCHEMBL7705935 | 0.77 | PRCP (0.66) | PRCPGAARECQLGID4 | |
| SCHEMBL7699907 | 0.77 | PRCP (0.66) | PRCPGAARECQLGID4TSHR | |
| SCHEMBL3066069 | 0.77 | PRCP (0.66) | PRCPGAARECQLGID4 | |
| Urea SCHEMBL27886692 | 0.76 | GAA (0.81) | PRCPGAARECQLGID4TSHR | |
| SCHEMBL28007086 | 0.75 | PRCP (0.76) | PRCPGAARECQLGID4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901488-B1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| EP-0901488-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| US-5866583-A | Substituted 2,4-diaminopyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |
| WO-1997043277-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-11-20 | — | — | WO | disclosed |