Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7697560 | 0.99 | PARP1 (0.37) | PARP1SSTR4HTR2BHTR7NPC1 | |
| SCHEMBL7702982 | 0.89 | PARP1 (0.43) | PARP1SSTR4NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL7697554 | 0.88 | PARP1 (0.42) | PARP1SSTR4NPC1RAB9AKMT2A | |
| SCHEMBL7701182 | 0.84 | PARP1 (0.43) | PARP1HTR2BHTR7SLC9A1 | |
| Hydrochloric Acid SCHEMBL7702267 | 0.82 | PARP1 (0.36) | PARP1HTR2BHTR7NPC1KMT2A | |
| SCHEMBL7701178 | 0.82 | PARP1 (0.41) | PARP1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL7702869 | 0.81 | KDM4E (0.33) | PARP1 | |
| Hydrochloric Acid SCHEMBL7696598 | 0.79 | RAD52 (0.38) | PARP1 | |
| SCHEMBL7697131 | 0.78 | PARP1 (0.46) | PARP1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL7702260 | 0.78 | PARP1 (0.36) | PARP1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346527-B1 | 1-BENZOXEPIN DERIVATIVES USED IN THE PREVENTION OF SODIUM AND HYDROGEN ION EXCHANGE; CARDIOVASCULAR, KIDNEY AND BRAIN DISORDER TREATMENT; ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-12 | — | — | US | claimed |
| EP-1073650-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-02-07 | — | — | EP | claimed |
| WO-1999055690-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-04 | — | — | WO | claimed |