Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.56 |
| ▸ | STS | P08842 | 7/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096655 | 0.87 | SHBG (0.70) | SHBGSTSAKR1C3HSD17B1CYP1B1 | |
| SCHEMBL975788 | 0.87 | SHBG (0.70) | SHBGSTSAKR1C3HSD17B1CYP1B1 | |
| SCHEMBL13725675 | 0.87 | SHBG (0.70) | SHBGSTSAKR1C3HSD17B1CYP1B1 | |
| SCHEMBL29446097 | 0.87 | SHBG (0.70) | SHBGSTSAKR1C3HSD17B1CYP1B1 | |
| SCHEMBL30887214 | 0.87 | SHBG (0.70) | SHBGSTSAKR1C3HSD17B1CYP1B1 | |
| SCHEMBL1258796 | 0.84 | SHBG (0.64) | SHBGSTSAKR1C3HSD17B1CYP1B1 | |
| Sulfamate SCHEMBL2451788 | 0.79 | STS (0.65) | SHBGSTSAKR1C3HSD17B1ESR1 | |
| SCHEMBL7043293 | 0.76 | STS (0.59) | SHBGSTSAKR1C3HSD17B1 | |
| SCHEMBL27561747 | 0.76 | SHBG (0.43) | SHBGSTSAKR1C3HTR2B | |
| SCHEMBL27561749 | 0.76 | SHBG (0.43) | SHBGSTSAKR1C3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355630-B1 | ANTIESTROGENS, HORMONE REPLACEMENTS AND OSTEOPOROSIS | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-12 | — | — | US | disclosed |
| US-6355630-B1 | ANTIESTROGENS, HORMONE REPLACEMENTS AND OSTEOPOROSIS | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-12 | — | — | US | disclosed |
| EP-1025116-A1 | ESTRA-1,3,5(10)-TRIENE-7ALPHA-THIOETHERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-09 | — | — | EP | disclosed |
| EP-1025116-A1 | ESTRA-1,3,5(10)-TRIENE-7ALPHA-THIOETHERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020646-A1 | ESTRA-1,3,5(10)-TRIENE-7ALPHA-THIOETHERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-04-29 | — | — | WO | disclosed |