Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.54 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260410 | 0.84 | RXRA (0.66) | S1PR1NOTUMTP53CYP3A4MAP4K4 | |
| SCHEMBL29426410 | 0.84 | RXRA (0.66) | S1PR1NOTUMTP53CYP3A4MAP4K4 | |
| SCHEMBL29012837 | 0.82 | RXRA (0.64) | S1PR1NOTUMTP53CYP3A4MAP4K4 | |
| SCHEMBL7705899 | 0.81 | KMT2A (0.57) | CYP3A4MAP4K4KDM4EALDH1A1HPGD | |
| SCHEMBL3793225 | 0.81 | CYP3A4 (0.79) | S1PR1NOTUMTP53CYP3A4MAP4K4 | |
| SCHEMBL30093058 | 0.81 | CYP3A4 (0.79) | S1PR1NOTUMTP53CYP3A4MAP4K4 | |
| SCHEMBL1337788 | 0.79 | TP53 (0.65) | NOTUMTP53CYP3A4MAP4K4FGFR2 | |
| SCHEMBL1337634 | 0.79 | TP53 (0.54) | S1PR1NOTUMTP53CYP3A4MAP4K4 | |
| SCHEMBL1335616 | 0.79 | TP53 (0.54) | S1PR1NOTUMTP53CYP3A4MAP4K4 | |
| SCHEMBL30338775 | 0.78 | RXRA (0.70) | NOTUMTP53CYP3A4MAP4K4FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |