Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563740 | 0.89 | FNTA (0.42) | FNTAFNTB | |
| SCHEMBL7565485 | 0.84 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL7561748 | 0.84 | FNTA (0.42) | FNTAFNTB | |
| SCHEMBL7692641 | 0.80 | CAPN1 (0.34) | FNTAFNTB | |
| SCHEMBL7567718 | 0.80 | FNTA (0.32) | FNTAFNTB | |
| SCHEMBL7563752 | 0.78 | FNTA (0.40) | FNTAFNTB | |
| SCHEMBL7564177 | 0.75 | FNTA (0.38) | FNTAFNTB | |
| SCHEMBL7562561 | 0.75 | ITGB3 (0.33) | FNTAFNTB | |
| SCHEMBL7561786 | 0.75 | KDM5A (0.35) | — | |
| SCHEMBL7562576 | 0.74 | FNTA (0.46) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342765-B1 | COMPOUNDS THAT INHIBIT FARNESYLATION OF MUTANT RAS GENE PRODUCTS; TREATING DISEASES, ESPECIALLY CANCER, WHICH ARE MEDIATED THROUGH FARNESYLATION OF RAS | ASTRAZENECA UK LIMITED (GB) | 2002-01-29 | — | — | US | disclosed |