Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699825 | 0.80 | DYRK1A (0.51) | DYRK1AADORA2AADORA1LRRK2CDK5 | |
| SCHEMBL8991102 | 0.77 | DYRK1A (0.56) | DYRK1AADORA2AADORA1LRRK2HSD17B10 | |
| SCHEMBL7695781 | 0.77 | DYRK1A (0.56) | DYRK1AADORA2AADORA1LRRK2CDK5 | |
| SCHEMBL7698534 | 0.77 | DYRK1A (0.60) | DYRK1AADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7699589 | 0.76 | DYRK1A (0.55) | DYRK1AADORA2AADORA1LRRK2CDK5 | |
| SCHEMBL7696582 | 0.75 | DYRK1A (0.57) | DYRK1AADORA2AADORA1LRRK2HSD17B10 | |
| SCHEMBL7697867 | 0.75 | DYRK1A (0.54) | DYRK1AADORA2AADORA1LRRK2CDK5 | |
| SCHEMBL7702669 | 0.75 | DYRK1A (0.57) | DYRK1AADORA2AADORA1LRRK2HSD17B10 | |
| SCHEMBL30582621 | 0.75 | DYRK1A (1.00) | DYRK1AADORA2AADORA1ADORA2BLRRK2 | |
| SCHEMBL26110102 | 0.75 | DYRK1A (1.00) | DYRK1AADORA2AADORA1ADORA2BLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |