Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | IKBKB | O14920 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701004 | 0.91 | KDM4E (0.59) | KDM4EGAANPC1RAB9AKMT2A | |
| SCHEMBL7695211 | 0.88 | KDM4E (0.53) | KDM4EGAANPC1RAB9AIKBKB | |
| SCHEMBL7703337 | 0.87 | GAA (0.49) | KDM4EGAANPC1RAB9AIKBKB | |
| SCHEMBL7703333 | 0.86 | KDM4E (0.64) | KDM4EGAANPC1RAB9AIKBKB | |
| SCHEMBL7699576 | 0.86 | KDM4E (0.48) | KDM4EGAANPC1RAB9AIKBKB | |
| SCHEMBL7703211 | 0.84 | KDM4E (0.49) | KDM4EGAANPC1RAB9AIKBKB | |
| SCHEMBL7693822 | 0.83 | NR1H4 (0.48) | KDM4EGAANPC1RAB9AIKBKB | |
| SCHEMBL7693950 | 0.82 | IKBKB (0.52) | KDM4EGAAIKBKBTRPV1TP53 | |
| SCHEMBL7699894 | 0.81 | IKBKB (0.54) | KDM4EGAANPC1RAB9AIKBKB | |
| SCHEMBL7699245 | 0.81 | KDM4E (0.52) | KDM4EGAANPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |