Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693982 | 0.91 | NLRP3 (0.44) | KDM4ERAB9ANPC1IKBKBNLRP3 | |
| SCHEMBL7694083 | 0.91 | KDM4E (0.59) | GAAKDM4ERAB9ANPC1POLB | |
| SCHEMBL7695211 | 0.88 | KDM4E (0.53) | GAAKDM4ERAB9ANPC1IKBKB | |
| SCHEMBL7697947 | 0.87 | KMT2A (0.47) | GAAKDM4ERAB9ANPC1IKBKB | |
| SCHEMBL7703553 | 0.87 | KDM4E (0.49) | GAAKDM4ERAB9ANPC1IKBKB | |
| SCHEMBL7703333 | 0.86 | KDM4E (0.64) | GAAKDM4ERAB9ANPC1IKBKB | |
| SCHEMBL7699576 | 0.86 | KDM4E (0.48) | GAAKDM4ERAB9ANPC1IKBKB | |
| SCHEMBL7703211 | 0.84 | KDM4E (0.49) | GAAKDM4ERAB9ANPC1IKBKB | |
| SCHEMBL7693950 | 0.82 | IKBKB (0.52) | GAAKDM4EIKBKBTRPV1TP53 | |
| SCHEMBL7699894 | 0.81 | IKBKB (0.54) | GAAKDM4ERAB9ANPC1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | claimed |
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |