Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.40 |
| ▸ | HRAS | P01112 | 1/20 | 0.40 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703752 | 1.00 | PDE4D (0.52) | PDE4DSLC6A2PTPN1SLC5A1TSHR | |
| SCHEMBL7703756 | 1.00 | PDE4D (0.52) | PDE4DSLC6A2PTPN1SLC5A1TSHR | |
| SCHEMBL6451124 | 1.00 | PDE4D (0.52) | PDE4DSLC6A2PTPN1SLC5A1TSHR | |
| SCHEMBL7703707 | 0.87 | PDE4D (0.43) | PDE4DSLC6A2TSHRCYP2C19 | |
| SCHEMBL7703704 | 0.87 | PDE4D (0.43) | PDE4DSLC6A2TSHRCYP2C19 | |
| SCHEMBL7703702 | 0.87 | PDE4D (0.43) | PDE4DSLC6A2TSHRCYP2C19 | |
| SCHEMBL9856549 | 0.83 | MAN1B1 (0.44) | PDE4D | |
| SCHEMBL9856460 | 0.82 | PDE4D (0.39) | PDE4DSLC6A2 | |
| SCHEMBL7703088 | 0.81 | PDE4D (0.41) | PDE4DSLC6A2 | |
| SCHEMBL7703090 | 0.81 | PDE4D (0.41) | PDE4DSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353095-B1 | OCTULSONIC ACID AND DERIVATIVES WITH AZO AND AMIDE | THE SCRIPPS RESEARCH INSTITUTE | 2002-03-05 | — | — | US | disclosed |
| WO-1993006227-A1 | KETOALDONIC ACIDS HAVING FORMED STEREOGENIC CENTERS OF R CONFIGURATION: METHODS AND COMPOSITIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-04-01 | — | — | WO | disclosed |