Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856549 | 0.89 | MAN1B1 (0.44) | PDE4DRECQLALDH1A1NPSR1KMT2A | |
| SCHEMBL7703749 | 0.82 | PDE4D (0.52) | PDE4DSLC6A2 | |
| SCHEMBL6451124 | 0.82 | PDE4D (0.52) | PDE4DSLC6A2 | |
| SCHEMBL7703752 | 0.82 | PDE4D (0.52) | PDE4DSLC6A2 | |
| SCHEMBL7703756 | 0.82 | PDE4D (0.52) | PDE4DSLC6A2 | |
| SCHEMBL7703707 | 0.81 | PDE4D (0.43) | PDE4DRECQLALDH1A1SLC6A2KMT2A | |
| SCHEMBL7703704 | 0.81 | PDE4D (0.43) | PDE4DRECQLALDH1A1SLC6A2KMT2A | |
| SCHEMBL7703702 | 0.81 | PDE4D (0.43) | PDE4DRECQLALDH1A1SLC6A2KMT2A | |
| SCHEMBL7703088 | 0.78 | PDE4D (0.41) | PDE4DRECQLALDH1A1SLC6A2NPSR1 | |
| SCHEMBL7703090 | 0.78 | PDE4D (0.41) | PDE4DRECQLALDH1A1SLC6A2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983726-A | Antitumor agents | SANOFI S.A. (FR) | 1991-01-08 | — | — | US | disclosed |
| US-4902791-A | ANTITUMOR AGENTS | SANOFI S.A. (FR) | 1990-02-20 | — | — | US | disclosed |