Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34096 | 0.85 | TGFBR1 (0.44) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL7945240 | 0.83 | TGFBR1 (0.43) | TGFBR1 | |
| SCHEMBL21597052 | 0.81 | TGFBR1 (0.44) | TGFBR1 | |
| SCHEMBL14678189 | 0.80 | TGFBR1 (0.44) | TGFBR1 | |
| Propionic Acid SCHEMBL14676809 | 0.79 | TGFBR1 (0.43) | TGFBR1 | |
| SCHEMBL8145684 | 0.77 | TGFBR1 (0.39) | TGFBR1 | |
| SCHEMBL1826412 | 0.76 | TGFBR1 (0.47) | TGFBR1HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL10909470 | 0.76 | TGFBR1 (0.47) | TGFBR1HDAC7HDAC8HDAC6HDAC9 | |
| Lactic Acid SCHEMBL8862042 | 0.76 | TGFBR1 (0.45) | TGFBR1ALDH1A1 | |
| SCHEMBL26105139 | 0.76 | TGFBR1 (0.38) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1334830-A | Hydrophilic ampholytic polymer | GOODRICH CO B F (US) | 2002-02-06 | — | — | CN | claimed |
| EP-1147138-A1 | HYDROPHILIC AMPHOLYTIC POLYMER | The B.F. Goodrich Company (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000039176-A1 | HYDROPHILIC AMPHOLYTIC POLYMER | THE B.F. GOODRICH COMPANY (US) | 2000-07-06 | — | — | WO | claimed |
| US-6361768-B1 | POLYMER FORMED BY COPOLYMERIZATION OF ANIONIC MONOMER HAVING CARBOXY-FUNCTIONAL GROUP, NON-QUATERNIZED CATIONIC MONOMER HAVING AMINO-FUNCTIONAL GROUP, NON-IONIC HYDROPHILIC MONOMER, HYDROPHOBIC MONOMER, OPTIONAL CROSSLINKING MONOMER | PMD HOLDINGS CORP. | 2002-03-26 | — | — | US | disclosed |
| CN-1334830-A | Hydrophilic ampholytic polymer | GOODRICH CO B F (US) | 2002-02-06 | — | — | CN | disclosed |
| EP-1147138-A1 | HYDROPHILIC AMPHOLYTIC POLYMER | The B.F. Goodrich Company (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000039176-A1 | HYDROPHILIC AMPHOLYTIC POLYMER | THE B.F. GOODRICH COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |