Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.79 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.32 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL9399607 | 0.92 | SLC7A5 (0.83) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL4261471 | 0.92 | SLC7A5 (0.83) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL7207898 | 0.90 | SLC7A5 (0.79) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL19548431 | 0.90 | SLC7A5 (0.79) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL756026 | 0.89 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL15602719 | 0.89 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL2213629 | 0.89 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL482773 | 0.89 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL935768 | 0.89 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL27571970 | 0.89 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901488-B1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| EP-0901488-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| US-5866583-A | Substituted 2,4-diaminopyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |
| WO-1997043277-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-11-20 | — | — | WO | disclosed |
| US-5246912-A | Liquid oil in water- or microemulsions | BEROL NOBEL (SUISSE) S.A. (CH) | 1993-09-21 | — | — | US | disclosed |
| US-4767448-A | STABILIZED MIXTURE OF PHENMEDIPHAM AND DESMEDIPHAM WITH SURFACTANT, MINERAL AND VEGETABLE OILS AND CARBOXYLIC ESTER OF AN ALCOHOL | KEMISK VAERK KOGE A/S (DK) | 1988-08-30 | — | — | US | disclosed |
| US-4748265-A | Process for the preparation of herbicidally active phenyl carbamates | KEMISK VAERK KOGE A/S (DK) | 1988-05-31 | — | — | US | disclosed |
| EP-0242888-A2 | Stabilized liquid herbicidal composition and process for its preparation | Hoechst Schering AgrEvo GmbH (DE) | 1987-10-28 | — | — | EP | disclosed |
| EP-0142670-A2 | A process for the preparation of known herbicidally active phenyl carbamates | BEROL NOBEL (SUISSE) S.A. (CH) | 1985-05-29 | — | — | EP | disclosed |
| WO-1985001286-A1 | A PROCESS FOR THE PREPARATION OF HERBICIDALLY ACTIVE PHENYL CARBAMATES AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME | KEMISK VA^ERK KO^/GE A/S (DK) | 1985-03-28 | — | — | WO | disclosed |
| EP-0037482-B1 | 3,4,5,6-TETRAHYDRO-1,2,4,6-THIATRIAZINE(3,5)DIONE-1,1-DIOXIDES, THEIR PREPARATION, HERBICIDES CONTAINING THEM, PROCESS FOR COMBATING GROWTH OF UNWANTED VEGETATION AND PROCESS FOR THE PREPARATION OF HERBICIDES | BASF Aktiengesellschaft (DE) | 1985-03-13 | — | — | EP | disclosed |
| EP-0037482-A2 | 3,4,5,6-Tetrahydro-1,2,4,6-thiatriazine(3,5)dione-1,1-dioxides, their preparation, herbicides containing them, process for combating growth of unwanted vegetation and process for the preparation of herbicides | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |