Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | CALML3 | P27482 | 1/20 | 0.49 |
| ▸ | SDHA | P31040 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 13/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687198 | 0.91 | F10 (0.48) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6687204 | 0.91 | F10 (0.48) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6687197 | 0.91 | F10 (0.48) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL27875818 | 0.90 | MAOA (0.61) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL27707418 | 0.90 | MAOA (0.61) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL483916 | 0.90 | MAOA (0.61) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7790986 | 0.87 | MAOB (0.53) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7157296 | 0.87 | MAOB (0.49) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7157301 | 0.87 | MAOB (0.49) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6691779 | 0.87 | MAOB (0.49) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362189-B1 | GRAMNEGATIVE, GRAMPOSITIVE BACTERIA | PHARMACIA AND UPJOHN COMPANY | 2002-03-26 | — | — | US | disclosed |