Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CALML3 | P27482 | 1/20 | 0.45 |
| ▸ | SDHA | P31040 | 1/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 9/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704365 | 1.00 | MAOB (0.46) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7704220 | 0.94 | MAOB (0.47) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7704225 | 0.94 | MAOB (0.47) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7712744 | 0.92 | MAOA (0.50) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7712747 | 0.92 | MAOA (0.50) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7712514 | 0.91 | MAOB (0.47) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7712509 | 0.91 | MAOB (0.47) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7710044 | 0.91 | MAOA (0.47) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7710043 | 0.91 | MAOA (0.47) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7703959 | 0.90 | MAOA (0.54) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362189-B1 | GRAMNEGATIVE, GRAMPOSITIVE BACTERIA | PHARMACIA AND UPJOHN COMPANY | 2002-03-26 | — | — | US | claimed |