SCHEMBL7704497

SCHEMBL7704497

C[C@@H](NC(=O)C(NC(=O)[C@H](C/C=C/c1ccc(Oc2ccccc2)c(F)c1)CC(=O)O)C(C)(C)C)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 20/20 0.51
MMP3 P08254 11/20 0.51
BMP1 P13497 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7107348 1.00 MMP2 (0.51) MMP2MMP3BMP1
SCHEMBL7107351 1.00 MMP2 (0.51) MMP2MMP3BMP1
SCHEMBL7112543 0.91 MMP2 (0.51) MMP2MMP3BMP1
SCHEMBL7709945 0.91 MMP2 (0.51) MMP2MMP3BMP1
SCHEMBL7112551 0.91 MMP2 (0.51) MMP2MMP3BMP1
SCHEMBL7113038 0.87 MMP2 (0.59) MMP2MMP3BMP1
SCHEMBL7113031 0.87 MMP2 (0.59) MMP2MMP3BMP1
SCHEMBL7113032 0.84 MMP2 (0.55) MMP2MMP3BMP1
SCHEMBL7114229 0.84 MMP2 (0.38) MMP2MMP3BMP1
SCHEMBL7114224 0.84 MMP2 (0.38) MMP2MMP3BMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6350907-B1 PEPTIDE ENZYME INHIBITORS PFIZER INC 2002-02-26 US disclosed