SCHEMBL770455

SCHEMBL770455

C=CCOC(=O)C(O)CC=C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SNCA P37840 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27493949 0.98 TSHR (0.40) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL29027440 0.98 TSHR (0.40) TSHRCYP3A4TDP1MAPTCACNA1B
Acrylamide SCHEMBL27670258 0.90 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL170054 0.82 CYP3A4 (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL9237824 0.82 CYP3A4 (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL2878558 0.80 ALDH1A1 (0.39) TSHRALDH1A1HSD17B10NPSR1CYP2C19
SCHEMBL7392048 0.80 MAPT (0.40) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL291912 0.80 CYP3A4 (0.38) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL7573463 0.80 CYP3A4 (0.38) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL17206201 0.80 CYP3A4 (0.38) TSHRCYP3A4TDP1MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114846078-B Inverse latex for cosmetic compositions combining tetrasodium salt of glutamic acid N, N-diacetic acid as chelating agent and polyelectrolyte comprising AMPS and acrylamide 化工产品开发公司SEPPIC 2024-03-29 CN claimed
CN-116390705-A Water-alcohol composition for hand disinfection 化工产品开发公司SEPPIC 2023-07-04 CN claimed
US-4751120-A CROSSLINKED POLYESTER COATING TOYO SEIKAN KAISHA, LTD. (JP) 1988-06-14 US claimed
US-4687689-A CROSSLINKING TOYO SEIKAN KAISHA, LTD. (JP) 1987-08-18 US claimed
JP-60031529-A None JP disclosed
CN-114846078-B Inverse latex for cosmetic compositions combining tetrasodium salt of glutamic acid N, N-diacetic acid as chelating agent and polyelectrolyte comprising AMPS and acrylamide 化工产品开发公司SEPPIC 2024-03-29 CN disclosed
CN-116390705-A Water-alcohol composition for hand disinfection 化工产品开发公司SEPPIC 2023-07-04 CN disclosed
US-20210138793-A1 LIQUID ABSORPTION SYSTEM, LIQUID ABSORPTION UNIT, AND IMAGE FORMING APPARATUS SEIKO EPSON CORPORATION (JP) 2021-05-13 US disclosed
US-20210122162-A1 LIQUID ABSORPTION SYSTEM, LIQUID ABSORPTION UNIT, AND IMAGE FORMING APPARATUS SEIKO EPSON CORPORATION (JP) 2021-04-29 US disclosed
US-20160213891-A1 Medical Dilation Element ZAMORE, ALAN 2016-07-28 US disclosed
US-9333278-B2 Medical dilation element Medtech Capital Ventures LLC (US) 2016-05-10 US disclosed
US-20120070599-A1 Reduced profile medical balloon element ZAMORE, ALAN 2012-03-22 US disclosed
US-4751120-A CROSSLINKED POLYESTER COATING TOYO SEIKAN KAISHA, LTD. (JP) 1988-06-14 US disclosed
US-4687689-A CROSSLINKING TOYO SEIKAN KAISHA, LTD. (JP) 1987-08-18 US disclosed
JP-S6031529-A MODIFIED POLYSTYRENE RESIN COMPOSITION OR MOLDING NISSIN ELECTRIC CO LTD 1985-02-18 JP disclosed
US-4383903-A POLYFUNCTIONAL AROMATIC CYANATE, ACRYLIC COMPOUND, POLYFUNCTIONAL MALEIMIDE, PHOTOINITIATOR MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-05-17 US disclosed
US-4297099-A BY PENETRATION AND CROSSLINKING DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed
US-4001368-A CURING DAI NIPPON TORYO CO., LTD. (JA) 1977-01-04 US disclosed
US-3968316-A Process for the surface treatment of unsaturated rubber NIPPON ZEON CO., LTD. (JA) 1976-07-06 US disclosed
JP-S0631529-A 0001-01-01 JP disclosed