SCHEMBL7704624

SCHEMBL7704624

NC(=O)C1CNC(=O)N1.NP(O)O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GLI1 P08151 1/20 0.33
RGS12 O14924 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3625362 0.92
SCHEMBL25041399 0.92
Hydroxyamine SCHEMBL6694548 0.74 CAD (0.43) RGS12TSHR
SCHEMBL873651 0.73
SCHEMBL16388867 0.73
SCHEMBL6602740 0.73
SCHEMBL6603156 0.73
SCHEMBL9392772 0.71
Lithium SCHEMBL29627538 0.71 CAD (0.44) TSHR
SCHEMBL25042354 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1208109-A2 NUCLEOSIDE ANALOGUES NYCOMED AMERSHAM PLC (GB) 2002-05-29 EP disclosed
WO-2001016150-A2 NUCLEOSIDE ANALOGUES AMERSHAM PLC (GB) 2001-03-08 WO disclosed