Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28994753 | 0.90 | TDP1 (0.62) | TDP1KMT2AMAPTALOX5AKR1C3 | |
| SCHEMBL689958 | 0.86 | KMT2A (0.51) | TDP1KMT2AKDM4EMEN1RECQL | |
| SCHEMBL688230 | 0.84 | KMT2A (0.50) | TDP1KMT2AACHESGMS1SGMS2 | |
| SCHEMBL688760 | 0.84 | KMT2A (0.50) | TDP1KMT2AACHESGMS1SGMS2 | |
| SCHEMBL27705565 | 0.83 | KMT2A (0.50) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL14988996 | 0.83 | PTGS2 (0.56) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL14988689 | 0.83 | KDM4E (0.70) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL14880259 | 0.83 | KMT2A (0.57) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL688269 | 0.82 | GAA (0.54) | SMN1; SMN2TDP1KMT2AKDM4EMEN1 | |
| SCHEMBL27686632 | 0.82 | KDM4E (0.49) | HDAC1HDAC3HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469193-B1 | THREE COMPONENT COUPLINGS OF ALIPHATIC ALCOHOLS, ALKYL HALIDES AND CARBON DIOXIDE IN THE PRESENCE OF CESIUM CARBONATE AND TETRABUTYLAMMONIUM IODIDE | UNIVERSITY OF SOUTH FLORIDA | 2002-10-22 | — | — | US | disclosed |
| WO-2000050376-A9 | EFFICIENT SYNTHESIS OF ALKYL CARBONATES | UNIV SOUTH FLORIDA (US) | 2001-10-11 | — | — | WO | disclosed |
| WO-2000050376-A2 | EFFICIENT SYNTHESIS OF ALKYL CARBONATES | UNIVERSITY OF SOUTH FLORIDA (US) | 2000-08-31 | — | — | WO | disclosed |